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(9) In one study on murine models, the authors commented that " CJC-1295 caused an increase in total pituitary RNA and GH mRNA, suggesting that proliferation of somatotroph cells had occurred, as confirmed by immunohistochemistry images

This addition allows the peptide to bind to albumin, a transporter protein commonly found in your bloodstream, and in doing so dramatically extends the half-life of the peptide: After a single injection of CJC-1295, there were dose-dependent increases in mean plasma GH concentrations by 2- to 10-fold for 6 d or more and in mean plasma IGF-I concentrations by 1.5- to 3-fold for 9 11 d